Crotchety retired doctor Isak Borg travels from Stockholm to Lund, Sweden, with his unhappy daughter-in-law, Marianne, in order to receive an honorary degree from his alma mater. Along the way, they encounter a series of hitchhikers, each of whom causes the elderly doctor to muse upon the pleasures and failures of his own life. These include the vivacious young Sara, a dead ringer for the doctor's own first love.
