Travelers Hansel and Zikmund sail from Africa to South America. On their journey to film, they capture clouds of locusts on the plains of Argentina's Chaco, a snake farm in Butantane, skyscrapers in Buenos Aires and Rio de Janeiro, a visit to lepers in Paraguay, waterfalls in Iguazu, a daring expedition to the jungles of the Marañon river basin to hunt skull hunters. an Indian settlement in Panama and the journey ends prematurely in Mexico amidst the ruins of ancient Indian temples and pyramid.
