A model queer activist and community advocate, Jesus prides himself in his work with the Seattle LGBT community. At the same time, Jesus is having unprotected sex and cheating on his long-time partner. Jesus's world implodes when he discovers that he is HIV positive, forcing him to confront his innermost fears, his relationship with his ex-boyfriend, and a future living with HIV. Faced with the unknown, Jesus is pulled from the brink of suicide by Sister Alysa Trailer, a drag queen nun who leads him down a path of self-discovery.
